Scientific Committee

The Scientific Committee (SciCom) is responsible for facilitating quality assurance aspects of all proposals for research that involves Princess Máxima Center patients, their data and/or material.

The goal of the committee is to ensure that the (pre-)clinical research carried out in the Princess Máxima Center is of the highest possible quality, that it is aligned with the mission of the center and complies with legal requirements, rules and regulations. The SciCom is an umbrella committee for all applications that are handled by the:

Clinical Research Committee (CRC)
Biobank and Data Access Committee (BDAC)

The Clinical Research Committee (CRC) is an independent committee responsible for the scientific assessment and quality assurance of all prospective clinical research proposals.

The Biobank and Data Access Committee (BDAC) is an independent committee responsible for the assessment of research applications where material and/or data is requested from the Princess Máxima Center Biobank.

Setting up a clinical trial or submitting a data request?

For Máxima employees: here you can find more information on the internal review procedures.

Scientists from external institutes may submit a research proposal in collaboration with a research group or clinical scientist of the Máxima center. Please contact one of our research groups to discuss the research proposal, or contact the SciCom for more information.

Committee members and Biobank

- Prof. dr. Michel Zwaan (chair, head of Trial and Data Center, clinical PI pharmaceutical research)
- Prof. dr. Josef Vormoor (clinical director Hemato-oncology)
- Dr. Paco Bautista Sirvent (clinical PI)
- Prof. dr. Wim Tissing (clinical PI supportive care)
- Prof. dr. Jan Molenaar (pre-clinical PI)
- Dr. Frederike Engels (pharmacist)
- Dr. Harm van Tinteren (head of Trial and Data Center, statistician)
- Prof. dr. Marta Fiocco (statistician)
- Ms. Odette Hemmer (client council)
- Ms. Natasha van Eijkelenburg (chair, pediatric oncologist)
- Prof. dr. Eelco Hoving (clinical director Neuro-oncology)
- Mr. Jan Lieverst (program manager clinical data)
- Prof. dr. Leendert Looijenga (principal investigator)
- Dr. Pascal Kusters (pathologist)
- Ms. Marjoleine de Lange (client council)
Patient materials that are collected during diagnosis, treatment and follow-up are registered and processed by the Laboratory for Childhood Cancer Pathology.
After routine diagnostics, excess material is in most cases available and can be used for future research. These biomaterials and the accompanying data are stored in the central Máxima Biobank, provided that informed consent for its use has been given.
The Biobank contains primary biomaterials (tissue, blood, bone marrow, etc.), derivatives thereof (DNA, RNA) as well as for instance clinical, genetic, and imaging data.